rs10220464
This is a downstream gene variant variant in the TDRD9 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
forced expiratory volume
Dapas M et al. “Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings.” Plos Genetics 19(1):e1010594 (2023)
Allele G
OR 0.31
p 2.0e-9
N 896
Small GWAS
multi-ancestry
About TDRD9
Predicted to enable ATP hydrolysis activity; RNA binding activity; and helicase activity. Involved in spermatogenesis. Located in cytoplasm and nucleus. Implicated in spermatogenic failure 30. [provided by Alliance of Genome Resources, Jul 2025]
View all TDRD9 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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