rs1022551537
This variant is located in the BCL11B gene.
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitter1 publicationAbout BCL11B
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
View all BCL11B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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