rs1035938
This is a synonymous variant in the BICRA gene — it does not change the protein's amino acid sequence.
▶Research that mentions this SNP (1)
▶Polymorphisms in GLTSCR1 and ERCC2 are associated with the development of oligodendrogliomasAssociationN=249Ping Yang et al.(2005)· Cancer
A case-control association study of 141 glioma cases and 108 controls identified polymorphisms in GLTSCR1 (rs1035938, T allele: 40% vs 27%, OR=3.4) and ERCC2 (rs1052555, T allele: 35% vs 18%) associated with oligodendroglioma development. Notably, carriers of the TT genotype at rs1035938 had significantly improved survival (77% at 2 years, 68% at 5 years vs 56% and 34% for other genotypes, P=0.02).
About BICRA
Enables transcription regulator activator activity. Involved in positive regulation of DNA-templated transcription. Located in nucleus. Part of SWI/SNF complex. Implicated in Coffin-Siris syndrome 12. [provided by Alliance of Genome Resources, Jul 2025]
View all BICRA variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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