rs10403273

This is a regulatory region variant variant in the HAPLN4 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Harris BHL et al. “New role of fat-free mass in cancer risk linked with genetic predisposition.” Scientific Reports 14(1):7270 (2024)

Allele G

OR 0.02

p 4.0e-10

N 342,566

Large GWAS

European

About HAPLN4

Predicted to be a structural constituent of synapse-associated extracellular matrix. Predicted to be involved in GABAergic synaptic transmission; nervous system development; and skeletal system development. Predicted to be located in extracellular region. Predicted to be active in extracellular space; perineuronal net; and synapse. [provided by Alliance of Genome Resources, Jul 2025]

View all HAPLN4 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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