rs10405382
This is a regulatory region variant variant in the DPY19L3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
mood disorder, major depressive disorder
Nagel M et al. “Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.” Nature Genetics 50(7):920-927 (2018)
Allele G
OR 0.02
p 7.0e-11
N 357,957
Meta-analysisLarge GWAS
European
About DPY19L3
Enables mannosyltransferase activity. Predicted to be involved in protein glycosylation. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all DPY19L3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…