rs10419976

This variant is located in the RDH13 gene.

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

platelet component distribution width

Allele T
OR 0.03
p 7.0e-26
N 394,642
Large GWAS
European

platelet volume

Allele T
OR 0.02
p 3.0e-15
N 394,642
Large GWAS
European

About RDH13

This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

View all RDH13 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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