rs10424405

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GWAS Catalog Trait Associations (41)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

monocyte count

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.06
p 4.0e-111
N 444,975
Large GWAS
multi-ancestry

probable RNA-binding protein 23 measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)
Allele G
OR 0.62
p 4.0e-104
N 3,301
Large GWAS
European

B melanoma antigen 2 measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)
Allele G
OR 0.54
p 1.0e-78
N 3,301
Large GWAS
European

cyclin-dependent kinase inhibitor 1b measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)
Allele G
OR 0.51
p 7.0e-68
N 3,301
Large GWAS
European

probable dimethyladenosine transferase measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)
Allele G
OR 0.50
p 6.0e-66
N 3,301
Large GWAS
European

chromobox protein homolog 7 measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)
Allele G
OR 0.50
p 5.0e-65
N 3,301
Large GWAS
European

NTF2-related export protein 1 measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)
Allele G
OR 0.48
p 4.0e-62
N 3,301
Large GWAS
European

caspase-8 measurement

Folkersen L et al. “Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.” Nature Metabolism 2(10):1135-1148 (2020)
Allele A
OR 0.21
p 4.0e-59
N 21,758
Large GWAS
European

thioredoxin reductase 1, cytoplasmic measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)
Allele G
OR 0.45
p 2.0e-53
N 3,301
Large GWAS
European

interleukin 18 measurement

Folkersen L et al. “Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.” Nature Metabolism 2(10):1135-1148 (2020)
Allele A
OR 0.16
p 1.0e-52
N 21,758
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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