rs10427255
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking initiation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele T
OR 0.02
p 9.0e-145
N 3,382,012
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
Erzurumluoglu AM et al. “Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.” Molecular Psychiatry 25(10):2392-2409 (2020)
Allele T
OR 0.02
p 3.0e-22
N 346,813
Meta-analysisLarge GWAS
multi-ancestry
social inhibition quality, attention deficit hyperactivity disorder, substance abuse
Karlsson Linnér R et al. “Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.” Nature Neuroscience 24(10):1367-1376 (2021)
Allele C
OR 0.01
p 3.0e-26
N 2,776,348
Large GWAS
European
autosomal dominant compelling helio-ophthalmic outburst syndrome
Wang M et al. “A genome-wide association study on photic sneeze reflex in the Chinese population.” Scientific Reports 9(1):4993 (2019)
Allele T
OR 1.68
p 6.0e-20
N 3,417
Large GWAS
East Asian
Sneeze
Eriksson N et al. “Web-based, participant-driven studies yield novel genetic associations for common traits.” Plos Genetics 6(6):e1000993 (2010)
Allele C
OR 1.32
p 1.0e-11
N 9,126
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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