rs10433310

This is a downstream gene variant variant in the MIF-AS1 gene.

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Research that mentions this SNP (1)

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Macrophage migration inhibitory factor gene polymorphisms and plasma levels in children with obstructive sleep apnea
AssociationN=614Abdelnaby Khalyfa et al.(2012)· Pediatric Pulmonology

Case-control study of 614 children (5-8 years) examining 28 SNPs in the MIF gene for association with obstructive sleep apnea (OSA). Children with OSA showed elevated plasma MIF levels compared to controls (p<0.02). The rs10433310 SNP showed significantly decreased minor allele frequency in OSA vs controls (p=0.03), and the GG genotype was associated with reduced insulin levels, hsCRP, and HOMA-IR, suggesting a protective effect against cardiometabolic risk markers.

Traits studied:Fasting insulinHigh-sensitivity C-reactive protein (hsCRP)Insulin resistance (HOMA-IR)Lipid profileObstructive Sleep ApneaPlasma MIF levels
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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