rs10484399

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

depressive symptom measurement

Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)

Allele G

OR 0.02

p 1.0e-20

N 1,067,913

Large GWAS

European

sarcoidosis

Rivera NV et al. “High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.” American Journal of Respiratory and Critical Care Medicine 193(9):1008-22 (2016)

Allele G

OR —

p 1.0e-16

N 1,048

Large GWAS

European

bipolar disorder, inflammatory bowel disease

Wang BR et al. “Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis.” Journal of Affective Disorders 348:167-174 (2024)

Allele A

OR 0.03

p 7.0e-14

N 473,423

Large GWAS

European

Inguinal hernia

Wei J et al. “Identification of fifty-seven novel loci for abdominal wall hernia development and their biological and clinical implications: results from the UK Biobank.” Hernia : the Journal of Hernias and Abdominal Wall Surgery 26(1):335-348 (2022)

Allele A

OR 1.11

p 2.0e-9

N 275,546

Major Consortium StudyLarge GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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