rs1048886
This is a protein-altering variant in the SDHAF4 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
type 2 diabetes mellitus
Sim X et al. “Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.” Plos Genetics 7(4):e1001363 (2011)
Allele G
OR 1.54
p 3.0e-8
N 8,135
Large GWAS
multi-ancestry
About SDHAF4
Predicted to enable enzyme activator activity. Involved in cellular respiration and mitochondrial respiratory chain complex II assembly. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
View all SDHAF4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…