rs10504119

This variant is located in the PXDNL gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

peroxidasin-like protein measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.19

p 3.0e-25

N 47,745

Large GWAS

European

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ClinVar annotation

Benign

2 submitters

PXDNL-related disorder; Thymoma; Lung cancer; Malignant lymphoma, large B-cell, diffuse; Sarcoma; Ovarian serous cystadenocarcinoma

View on ClinVar →

About PXDNL

Predicted to enable heme binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be located in endoplasmic reticulum; extracellular region; and plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]

View all PXDNL variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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