rs10506525

This is a intron variant variant in the MSRB3 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

odontogenesis

Pillas D et al. “Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.” Plos Genetics 6(2):e1000856 (2010)

Allele C

OR —

p 6.0e-9

N 5,919

Large GWAS

European

snoring measurement

Zhu Y et al. “A genome-wide association study based on the China Kadoorie Biobank identifies genetic associations between snoring and cardiometabolic traits.” Communications Biology 7(1):305 (2024)

Allele T

OR 0.06

p 1.0e-8

N 76,403

Large GWAS

East Asian

About MSRB3

The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]

View all MSRB3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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