rs1056524
This is a synonymous variant in the C3orf22 gene — it does not change the protein's amino acid sequence.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 0.27
p 1.0e-83
N 10,708
Large GWAS
European
blood protein amount
Suhre K et al. “A genome-wide association study of mass spectrometry proteomics using a nanoparticle enrichment platform.” Nature Genetics 57(12):2987-2996 (2025)
Allele A
OR 0.47
p 9.0e-35
N 1,257
Large GWAS
multi-ancestry
inter-alpha-trypsin inhibitor heavy chain H1 measurement
Allele A
OR 0.28
p 8.0e-26
N 3,301
Large GWAS
European
About C3orf22
Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all C3orf22 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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