rs10744774

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

platelet count

Chen MH et al. “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.” Cell 182(5):1198-1213.e14 (2020)

Allele A

OR 0.10

p —

N 542,827

Large GWAS

European

phospholipids in medium HDL measurement

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)

Allele A

OR 0.02

p 8.0e-14

N 450,015

Large GWAS

multi-ancestry

tumor necrosis factor amount

Yuan S et al. “Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study.” Ebiomedicine 59:102956 (2020)

Allele A

OR 0.04

p 7.0e-11

N 30,912

Large GWAS

European

platelet crit

Xiang R et al. “Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and prediction.” Nature Communications 16(1):4260 (2025)

Allele C

OR 0.02

p 1.0e-9

N 390,802

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…