rs10753232
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
neuroimaging measurement
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele T
OR 0.09
p 2.0e-21
N 21,282
Major Consortium StudyLarge GWAS
European
thalamus volume
Elvsåshagen T et al. “The genetic architecture of the human thalamus and its overlap with ten common brain disorders.” Nature Communications 12(1):2909 (2021)
Allele T
OR 0.06
p 5.0e-12
N 30,114
Large GWAS
European
amount of iron in brain
Casanova F et al. “MRI-derived brain iron, grey matter volume, and risk of dementia and Parkinson's disease: Observational and genetic analysis in the UK Biobank cohort.” Neurobiology of Disease 197:106539 (2024)
Allele C
OR 0.04
p 9.0e-11
N 39,533
Major Consortium StudyLarge GWAS
European
amygdala volume
Mufford MS et al. “The Genetic Architecture of Amygdala Nuclei.” Biological Psychiatry 95(1):72-84 (2024)
Allele T
OR 0.23
p 4.0e-10
N 36,352
Large GWAS
multi-ancestry
cortical thickness
Zhukovsky P et al. “Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression.” Nature Communications 15(1):5207 (2024)
Allele T
OR —
p 4.0e-9
N 34,542
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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