rs10761244

This is a intron variant variant in the PHF2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

social interaction measurement

Bralten J et al. “Genetic underpinnings of sociability in the general population.” Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 46(9):1627-1634 (2021)

Allele C

OR —

β 0.012

p 8.0e-9

N 342,461

Large GWAS

European

About PHF2

This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. [provided by RefSeq, Jul 2008]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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