rs10768140
This is a intron variant variant in the PAMR1 gene.
▶Research that mentions this SNP (1)
▶Admixture mapping of prostate cancer in African Americans participating in the North Carolina‐Louisiana Prostate Cancer Project (PCaP)AssociationN=990Jeannette T. Bensen et al.(2014)· The Prostate
Admixture mapping in 990 African American prostate cancer cases using 1,438 ancestry informative markers identified a significant locus on chromosome 8q24.21 (rs12543473, P=0.0011) confirming prior findings, and discovered a novel European ancestry signal on chromosome 11p13 (rs10768140, P=0.0004) associated with prostate cancer risk. The study demonstrates that ancestry-specific genetic variants may underlie racial disparities in prostate cancer incidence in African Americans.
About PAMR1
Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
View all PAMR1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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