rs10801582

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

protein measurement

Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)

Allele A

OR 0.30

p 6.0e-86

N 10,708

Large GWAS

European

hemopexin measurement

Suhre K et al. “Connecting genetic risk to disease end points through the human blood plasma proteome.” Nature Communications 8:14357 (2017)

Allele A

OR 0.74

p 1.0e-49

N 997

Small GWAS

multi-ancestry

complement factor H-related protein 5 measurement

Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)

Allele A

OR 0.22

p 4.0e-42

N 10,708

Large GWAS

European

complement factor H-related protein 4 measurement

Cipriani V et al. “Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations.” American Journal of Human Genetics 108(8):1385-1400 (2021)

Allele A

OR 1.48

p 1.0e-12

N 252

Small GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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