rs10811650

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

coronary artery disease

Matsunaga H et al. “Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease.” Circulation. Genomic and Precision Medicine 13(3):e002670 (2020)

Allele G

OR 1.15

p 2.0e-71

N 392,241

Meta-analysisLarge GWAS

multi-ancestry

coronary artery calcification

Kavousi M et al. “Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.” Nature Genetics 55(10):1651-1664 (2023)

Allele A

OR 0.20

p 2.0e-27

N 36,720

Large GWAS

multi-ancestry

cutaneous melanoma, hair color

Landi MT et al. “Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility.” Nature Genetics 52(5):494-504 (2020)

Allele A

OR —

p 2.0e-18

N 764,610

Large GWAS

European

breast carcinoma

Michailidou K et al. “Association analysis identifies 65 new breast cancer risk loci.” Nature 551(7678):92-94 (2017)

Allele G

OR 0.05

p 2.0e-13

N 139,274

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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