rs10814274

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

glycosyl-N-stearoyl-sphingosine (d18:1/18:0) measurement

Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)

Allele T

OR 0.14

p 6.0e-20

N 8,233

Large GWAS

European

Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)

Allele T

OR 0.12

p 7.0e-15

N 8,809

Large GWAS

European

migraine disorder, type 2 diabetes mellitus

Islam MR et al. “Genetic Overlap Analysis Identifies a Shared Etiology between Migraine and Headache with Type 2 Diabetes.” Genes 13(10) (2022)

Allele T

OR 0.98

p 7.0e-9

N 1,771,473

Large GWAS

European

level of ceramide

Cadby G et al. “Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.” Nature Communications 13(1):3124 (2022)

Allele T

OR 0.13

p 2.0e-8

N 4,492

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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