rs10817938
This is a coding sequence variant variant in the PTCSC2 gene.
▶Research that mentions this SNP (1)
▶Comprehensive pathway‐based interrogation of genetic variations in the nucleotide excision DNA repair pathway and risk of bladder cancerAssociationN=1,606Jinliang Xing et al.(2012)· Cancer
A comprehensive pathway-based case-control study of 803 bladder cancer cases and 803 controls evaluating 207 SNPs in 26 nucleotide excision repair (NER) pathway genes. Seventeen SNPs were significantly associated with bladder cancer risk at P<0.05, with seven retaining noteworthiness by Bayesian false discovery probability. The most significant finding was rs11132186 in ING2 (OR=0.52, 95% CI 0.32-0.83, P=0.005). Four ING2 variants and two DDB2 variants were significantly associated with altered bladder cancer risk, with evidence for gene-smoking and gene-gene interactions.
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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