rs10850722
This is a intron variant variant in the RNFT2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
hippocampal CA4 volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele G
OR 0.08
p 3.0e-9
N 38,977
Large GWAS
European, East Asian
subiculum volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele G
OR 0.07
p 2.0e-8
N 38,977
Large GWAS
European, East Asian
About RNFT2
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in positive regulation of ERAD pathway. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all RNFT2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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