rs10851907

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GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

peripheral arterial disease

van Zuydam NR et al. “Genome-Wide Association Study of Peripheral Artery Disease.” Circulation. Genomic and Precision Medicine 14(5):e002862 (2021)
Allele A
OR 1.06
p 1.0e-35
N 461,634
Large GWAS
multi-ancestry
Klarin D et al. “Genome-wide association study of peripheral artery disease in the Million Veteran Program.” Nature Medicine 25(8):1274-1279 (2019)
Allele A
OR 1.06
p 1.0e-13
N 243,060
Major Consortium StudyLarge GWAS
multi-ancestry

asphyxia, Hypoxemia

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.12
p 2.0e-23
N 435,319
Major Consortium StudyLarge GWAS
European

smoking behavior trait

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.03
p 1.0e-17
N 154,894
Major Consortium StudyLarge GWAS
European

family history of lung cancer

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.10
p 8.0e-16
N 400,487
Major Consortium StudyLarge GWAS
multi-ancestry

pneumonia

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.05
p 3.0e-13
N 599,837
Major Consortium StudyLarge GWAS
multi-ancestry

dental caries, dentures

Shungin D et al. “Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.” Nature Communications 10(1):2773 (2019)
Allele A
OR 0.02
p 1.0e-9
N 487,823
Large GWAS
multi-ancestry

dentures

Shungin D et al. “Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.” Nature Communications 10(1):2773 (2019)
Allele A
OR 0.03
p 1.0e-9
N 461,031
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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