rs10896017
This is a regulatory region variant variant in the FAM89B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of latent-transforming growth factor beta-binding protein 3 in blood
Png G et al. “Mapping the serum proteome to neurological diseases using whole genome sequencing.” Nature Communications 12(1):7042 (2021)
Allele T
OR 0.60
p 5.0e-25
N 2,917
Large GWAS
European
About FAM89B
Predicted to enable transcription corepressor binding activity. Predicted to be involved in establishment of cell polarity; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and positive regulation of cell migration. Predicted to be located in cell projection. Predicted to be active in cytoplasm and lamellipodium. [provided by Alliance of Genome Resources, Jul 2025]
View all FAM89B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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