rs10901814

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GWAS Catalog Trait Associations (10)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain attribute

van der Meer D et al. “The genetic architecture of human cortical folding.” Science Advances 7(51):eabj9446 (2021)
Allele G
OR 28.24
p 2.0e-175
N 33,748
Large GWAS
European

cortical thickness

van der Meer D et al. “The genetic architecture of human cortical folding.” Science Advances 7(51):eabj9446 (2021)
Allele G
OR 17.45
p 3.0e-68
N 33,748
Large GWAS
European

brain connectivity attribute

Sha Z et al. “Genetic architecture of the white matter connectome of the human brain.” Science Advances 9(7):eadd2870 (2023)
Allele G
OR 11.96
p 6.0e-33
N 30,810
Large GWAS
European

neuroimaging measurement

Bhatt RR et al. “The Genetic Architecture of the Human Corpus Callosum and its Subregions.” Nature Communications 16(1):9708 (2025)
Allele C
OR 1.70
p 2.0e-24
N 46,685
Large GWAS
European

brain volume

Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele C
OR 0.07
p 2.0e-14
N 21,282
Major Consortium StudyLarge GWAS
European

hippocampal CA1 volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.05
p 4.0e-13
N 38,977
Large GWAS
European, East Asian

dentate gyrus volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.06
p 2.0e-16
N 38,977
Large GWAS
European, East Asian

hippocampal CA3 volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.07
p 1.0e-20
N 38,977
Large GWAS
European, East Asian

hippocampal CA4 volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.06
p 3.0e-16
N 38,977
Large GWAS
European, East Asian

hippocampal volume

Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.05
p 2.0e-13
N 38,977
Large GWAS
European, East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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