rs10919543
This is a downstream gene variant variant.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
low affinity immunoglobulin gamma Fc region receptor III-B measurement
Allele G
OR 0.44
p 3.0e-67
N 3,301
Large GWAS
European
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele G
OR 0.42
p 2.0e-48
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
leukocyte quantity
Orrù V et al. “Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.” Nature Genetics 52(10):1036-1045 (2020)
Allele G
OR 0.31
p 1.0e-29
N 3,596
Large GWAS
European
level of adhesion G protein-coupled receptor E1 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.04
p 3.0e-12
N 47,745
Large GWAS
European
Takayasu arteritis
Saruhan-Direskeneli G et al. “Identification of multiple genetic susceptibility loci in Takayasu arteritis.” American Journal of Human Genetics 93(2):298-305 (2013)
Allele G
OR 1.81
p 6.0e-12
N 1,447
Large GWAS
multi-ancestry
blood protein amount
Orrù V et al. “Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.” Nature Genetics 52(10):1036-1045 (2020)
Allele G
OR 0.15
p 3.0e-8
N 3,113
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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