rs10935473
▶GWAS Catalog Trait Associations (42)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (42)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
t-cell surface glycoprotein CD5 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.45
p 1.0e-303
N 10,708
Large GWAS
European
uromodulin measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.45
p 5.0e-295
N 10,708
Large GWAS
European
level of tyrosine-protein kinase receptor Tie-1 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.19
p 2.0e-287
N 47,745
Large GWAS
European
level of MHC class I polypeptide-related sequence A in blood, level of MHC class I polypeptide-related sequence B in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.05
p 3.0e-257
N 47,745
Large GWAS
European
vascular endothelial growth factor receptor 3 level
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.40
p 6.0e-227
N 10,708
Large GWAS
European
Allele T
OR —
β 0.690
p 1.0e-215
N 3,301
Large GWAS
European
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele T
OR 0.72
p 2.0e-155
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
Quintanilha JCF et al. “Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).” Bmc Genomics 25(1):473 (2024)
Allele T
OR —
β 0.290
p 6.0e-39
N 869
Small GWAS
European
vascular endothelial growth factor receptor 2 level
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.13
p 4.0e-171
N 47,745
Large GWAS
European
amphoterin-induced protein 2 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.15
p 8.0e-164
N 47,745
Large GWAS
European
level of interleukin-6 receptor subunit beta in blood serum
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.15
p 4.0e-156
N 47,745
Large GWAS
European
sialic acid-binding Ig-like lectin 9 amount
Png G et al. “Mapping the serum proteome to neurological diseases using whole genome sequencing.” Nature Communications 12(1):7042 (2021)
Allele T
OR 0.57
p 3.0e-125
N 2,893
Large GWAS
European
tyrosine-protein kinase receptor Tie-1, soluble measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.28
p 1.0e-102
N 10,708
Large GWAS
European
Allele T
OR —
β 0.270
p 9.0e-29
N 3,301
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…