rs10946507

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)

Allele A

OR 0.01

p 1.0e-84

N 5,314,291

Large GWAS

European, Hispanic or Latin American, East Asian, African unspecified, South Asian

Astigmatism

Shah RL et al. “Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci.” Human Genetics 137(11-12):881-896 (2018)

Allele G

OR 1.08

p 2.0e-9

N 88,005

Major Consortium StudyLarge GWAS

European

cerebellar volume measurement

Moberget T et al. “The genetic architecture of human cerebellar morphology supports a key role for the cerebellum in human evolution and psychopathology.” Communications Biology 9(1) (2026)

Allele A

OR —

p 2.0e-9

N 27,302

Large GWAS

European

refractive error, self reported educational attainment

Fan Q et al. “Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.” Nature Communications 7:11008 (2016)

Allele A

OR —

p 2.0e-8

N 50,351

Meta-analysisLarge GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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