rs10981377

This is a regulatory region variant variant in the HSDL2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

protein measurement

Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)

Allele T

OR 0.18

p 4.0e-40

N 10,708

Large GWAS

European

About HSDL2

Predicted to enable oxidoreductase activity. Involved in cholesterol homeostasis. Located in mitochondrion and peroxisome. [provided by Alliance of Genome Resources, Jul 2025]

View all HSDL2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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