rs10995201

This is a intron variant variant.

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

breast cancer, chronotype measurement

Wu X et al. “Using human genetics to understand the phenotypic association between chronotype and breast cancer.” Journal of Sleep Research 33(3):e13973 (2024)
Allele A
OR —
p 1.0e-56
N 696,907
Large GWAS
European

breast carcinoma

Shu X et al. “Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants.” Nature Communications 11(1):1217 (2020)
Allele A
OR 1.14
p 5.0e-52
N 277,932
Large GWAS
multi-ancestry
Michailidou K et al. “Association analysis identifies 65 new breast cancer risk loci.” Nature 551(7678):92-94 (2017)
Allele A
OR 1.11
p 2.0e-51
N 139,274
Large GWAS
multi-ancestry

estrogen-receptor negative breast cancer

Milne RL et al. “Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.” Nature Genetics 49(12):1767-1778 (2017)
Allele A
OR 1.08
p 2.0e-9
N 72,261
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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