rs11014002

This is a coding sequence variant variant in the KIAA1217 gene.

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Research that mentions this SNP (2)

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Polymorphism rs2682818 in miR‐618 is associated with colorectal cancer susceptibility in a Han Chinese population
AssociationN=1,762Yuetong Chen et al.(2018)· Cancer Medicine

A case-control study of 878 colorectal cancer patients and 884 controls in a Han Chinese population found that SNP rs2682818 (C>A) in the miR-618 gene was associated with decreased CRC susceptibility. The AA and AC/AA genotypes showed protective effects with OR=0.54 (95% CI=0.37-0.79) and OR=0.82 (95% CI=0.68-0.99), respectively, compared to the CC genotype.

Traits studied:Colorectal cancer
PubMedDOIMetascience Observatory
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The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucose
AssociationN=73,014Mohsen Ghanbari et al.(2015)· Obesity

Two miRNA genetic variants were identified as significantly associated with cardiometabolic phenotypes: rs11614913 in miR-196a2 associated with waist-to-hip ratio (P=1.7e-25), and rs174561 in miR-1908 associated with lipid and glucose traits. Functional analyses revealed these variants affect pre-miRNA processing and regulate target genes involved in fat distribution and lipid metabolism.

Traits studied:HDL-cholesterolLDL-cholesterolblood pressurebody mass indexcardiometabolic phenotypesfasting glucosetotal cholesteroltriglycerideswaist-to-hip ratio
PubMedDOIMetascience Observatory

About KIAA1217

Predicted to be involved in embryonic skeletal system development. Located in centrosome. [provided by Alliance of Genome Resources, Jul 2025]

View all KIAA1217 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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