rs11057841
This is a intron variant variant in the SCARB1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of N-acetylneuraminate lyase in blood serum
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.11
p 8.0e-49
N 47,745
Large GWAS
European
lipoprotein-associated phospholipase A(2) measurement
Chu AY et al. “Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.” Circulation. Cardiovascular Genetics 5(6):676-85 (2012)
Allele T
OR 0.03
p 6.0e-14
N 6,851
Large GWAS
European
About SCARB1
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2 and facilitates cell entry by the virus, SARS-CoV2. [provided by RefSeq, Oct 2021]
View all SCARB1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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