rs11064321
This is a regulatory region variant variant in the PIANP gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
PILR alpha-associated neural protein measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.14
p 1.0e-22
N 10,708
Large GWAS
European
Allele C
OR 0.21
p 8.0e-15
N 3,301
Large GWAS
European
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele C
OR 0.24
p 6.0e-13
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
About PIANP
This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Sep 2011]
View all PIANP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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