rs11066359

This is a intron variant variant in the RPH3A gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alcohol consumption quality

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele T

OR 0.16

p 4.9e-324

N 2,965,643

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

body height

Chiou JS et al. “Your height affects your health: genetic determinants and health-related outcomes in Taiwan.” Bmc Medicine 20(1):250 (2022)

Allele C

OR 0.03

p 1.0e-8

N 67,452

Large GWAS

East Asian

About RPH3A

The protein encoded by this gene is thought to be an effector for RAB3A, which is a small G protein that acts in the late stages of neurotransmitter exocytosis. The encoded protein may be involved in neurotransmitter release and synaptic vesicle traffic. [provided by RefSeq, Dec 2016]

View all RPH3A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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