rs1108842
This variant is located in the GNL3 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
intelligence
Hill WD et al. “A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.” Molecular Psychiatry 24(2):169-181 (2019)
Allele A
OR 0.02
p 8.0e-9
N 248,482
Large GWAS
European
adiponectin measurement
Sarsani V et al. “A cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin.” Hgg Advances 5(1):100252 (2024)
Allele C
OR 0.03
p 2.0e-15
N 38,609
Meta-analysisLarge GWAS
European
Dastani Z et al. “Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.” Plos Genetics 8(3):e1002607 (2012)
Allele C
OR 0.03
p 1.0e-13
N 29,347
Meta-analysisLarge GWAS
European
About GNL3
The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
View all GNL3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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