rs111444407
This is a intron variant variant in the NCAN gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bipolar disorder
Li HJ et al. “Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis.” Jama Psychiatry 78(3):320-330 (2021)
Allele T
OR 1.10
p 5.0e-10
N 58,182
Meta-analysisLarge GWAS
multi-ancestry
Stahl EA et al. “Genome-wide association study identifies 30 loci associated with bipolar disorder.” Nature Genetics 51(5):793-803 (2019)
Allele T
OR 1.10
p 1.0e-9
N 51,710
Large GWAS
European
bipolar I disorder
Stahl EA et al. “Genome-wide association study identifies 30 loci associated with bipolar disorder.” Nature Genetics 51(5):793-803 (2019)
Allele T
OR 1.13
p 3.0e-9
N 46,237
Large GWAS
European
bipolar disorder, ulcerative colitis
Wang BR et al. “Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis.” Journal of Affective Disorders 348:167-174 (2024)
Allele C
OR 0.02
p 4.0e-9
N 459,441
Large GWAS
European
About NCAN
Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002]
View all NCAN variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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