rs11160570
This variant is located in the EVL gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
white matter hyperintensity measurement
Persyn E et al. “Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants.” Nature Communications 11(1):2175 (2020)
Allele T
OR 6.67
p 6.0e-13
N 45,204
Large GWAS
multi-ancestry
About EVL
Predicted to enable SH3 domain binding activity and profilin binding activity. Involved in negative regulation of epithelial cell migration; negative regulation of ruffle assembly; and positive regulation of stress fiber assembly. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all EVL variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…