rs111632177

This is a downstream gene variant variant in the CHPF2 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of Fc receptor-like B in blood

Allele A
OR 0.09
p 6.0e-38
N 47,745
Large GWAS
European

level of immunoglobulin lambda constant 2 (human) in blood

Allele A
OR 0.07
p 2.0e-13
N 47,745
Large GWAS
European

serum IgG glycosylation measurement

Landini A et al. Genetic regulation of post-translational modification of two distinct proteins. Nature Communications 13(1):1586 (2022)
Allele A
OR 0.32
p 4.0e-12
N 2,020
Large GWAS
European

About CHPF2

Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all CHPF2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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