rs11189591

This is a upstream gene variant variant in the PYROXD2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

arginine measurement

Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)

Allele T

OR 0.11

p 2.0e-23

N 14,296

Large GWAS

European

About PYROXD2

Predicted to enable oxidoreductase activity. Involved in mitochondrion organization. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Jul 2025]

View all PYROXD2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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