rs11191683
This is a intron variant variant in the PDCD11 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
insomnia
Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele T
OR 0.01
p 1.0e-9
N 2,365,010
Meta-analysisLarge GWAS
European
intracranial volume measurement
Klein M et al. “Genetic Markers of ADHD-Related Variations in Intracranial Volume.” The American Journal of Psychiatry 176(3):228-238 (2019)
Allele T
OR 6.05
p 1.0e-9
N 24,024
Large GWAS
European
About PDCD11
PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008]
View all PDCD11 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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