rs11202051

This is a intron variant variant in the ANXA11 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

sarcoidosis

Yuan S et al. “GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis.” Nature Communications 16(1):2481 (2025)
Allele A
OR 0.78
p 6.0e-58
N 1,536,622
Large GWAS
multi-ancestry
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.32
p 3.0e-16
N 451,032
Major Consortium StudyLarge GWAS
European

About ANXA11

This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, Dec 2015]

View all ANXA11 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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