rs11205277

This is a downstream gene variant variant.

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height, body weights and measures

Galván-Femenía I et al. “Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.” Journal of Medical Genetics 55(11):765-778 (2018)
Allele G
OR 0.03
p 1.0e-85
N 4,988
Large GWAS
European

body height

Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele G
OR 0.05
p 1.0e-80
N 472,730
Large GWAS
East Asian
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.03
p 3.0e-33
N 165,056
Large GWAS
East Asian
Lango Allen H et al. “Hundreds of variants clustered in genomic loci and biological pathways affect human height.” Nature 467(7317):832-8 (2010)
Allele G
OR —
β 0.046
p 5.0e-32
N 133,653
Large GWAS
European
He M et al. “Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.” Human Molecular Genetics 24(6):1791-800 (2015)
Allele G
OR 0.05
p 1.0e-12
N 36,227
Meta-analysisLarge GWAS
East Asian
Gudbjartsson DF et al. “Many sequence variants affecting diversity of adult human height.” Nature Genetics 40(5):609-15 (2008)
Allele G
OR 5.10
p 1.0e-10
N 30,968
Large GWAS
European

fat pad mass

Harris BHL et al. “New role of fat-free mass in cancer risk linked with genetic predisposition.” Scientific Reports 14(1):7270 (2024)
Allele G
OR 0.02
p 1.0e-18
N 337,196
Large GWAS
European

BMI-adjusted waist circumference

Justice AE et al. “Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.” Nature Communications 8:14977 (2017)
Allele A
OR 0.03
p 4.0e-12
N 152,914
Meta-analysisLarge GWAS
multi-ancestry
Shungin D et al. “New genetic loci link adipose and insulin biology to body fat distribution.” Nature 518(7538):187-196 (2015)
Allele A
OR 0.03
p 1.0e-8
N 143,480
Large GWAS
multi-ancestry

smoking behavior, BMI-adjusted waist circumference

Justice AE et al. “Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.” Nature Communications 8:14977 (2017)
Allele A
OR —
p 4.0e-14
N 195,506
Meta-analysisLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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