rs11212662

This variant is located in the POGLUT3 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

platelet count

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 0.04

p 5.0e-42

N 407,168

Major Consortium StudyLarge GWAS

European

triple-negative breast cancer, luminal A breast carcinoma

Sun X et al. “Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants That Confer Risk for Breast Cancer.” Cancer Research 84(15):2533-2548 (2024)

Allele G

OR 0.02

p 5.0e-8

N 77,214

Large GWAS

European

About POGLUT3

Enables UDP-glucosyltransferase activity and UDP-xylosyltransferase activity. Involved in protein O-linked glycosylation via serine. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endomembrane system. [provided by Alliance of Genome Resources, Jul 2025]

View all POGLUT3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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