rs112313064
This is a synonymous variant in the FUT6 gene — it does not change the protein's amino acid sequence.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
response to COVID-19 vaccine, COVID-19
Alcalde-Herraiz M et al. “Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank.” Nature Communications 15(1):8739 (2024)
Allele C
OR 1.06
p 1.0e-22
N 315,323
Major Consortium StudyLarge GWAS
European
About FUT6
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
View all FUT6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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