rs11264295
This variant is located in the ZBTB7B gene.
▶ClinVar annotation
Benign★★★☆
2 submitters1 publicationAbout ZBTB7B
This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
View all ZBTB7B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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