rs11279109
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▶Research that mentions this SNP (1)
▶Genetic analysis of the relation of telomere length‐related gene (RTEL1) and coronary heart disease riskAssociationN=1,199Shijuan Lu et al.(2019)· Molecular Genetics & Genomic Medicine
Genetic analysis of the relation of telomere length‐related gene (RTEL1) and coronary heart disease risk
AssociationN=1,199Shijuan Lu et al.(2019)· Molecular Genetics & Genomic Medicine
This case-control study examined 5 SNPs in the RTEL1 gene (regulator of telomere elongation helicase 1) in 596 coronary heart disease (CHD) patients and 603 healthy controls from a Chinese Han population. Two SNPs showed protective associations: rs6010620 (OR = 0.78, 95% CI = 0.65-0.93, p = 0.005) and rs4809324 (OR = 0.08, 95% CI = 0.04-0.16, p = 2.74E-21). Haplotype analysis revealed the 'GTT' haplotype of three RTEL1 SNPs was associated with significantly decreased CHD risk (OR = 0.03, 95% CI = 0.01-0.12, p < 0.0001).
Traits studied:CHDCoronary heart disease
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