rs112881196
▶GWAS Catalog Trait Associations (12)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (12)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
X-11444 measurement
Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele C
OR 0.71
p 2.0e-165
N 14,296
Large GWAS
European
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele C
OR 0.94
p 1.0e-45
N 6,136
Large GWAS
European
X-11470 measurement
Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele C
OR 0.55
p 5.0e-89
N 14,296
Large GWAS
European
metabolite measurement
Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele C
OR 0.46
p 5.0e-65
N 14,296
Large GWAS
European
etiocholanolone glucuronide measurement
Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele C
OR 0.41
p 9.0e-56
N 14,296
Large GWAS
European
estradiol measurement
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele G
OR 0.02
p 6.0e-30
N 206,927
Large GWAS
European
Schmitz D et al. “Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density.” The Journal of Clinical Endocrinology and Metabolism 106(11):e4471-e4486 (2021)
Allele G
OR 1.35
p 9.0e-24
N 147,690
Large GWAS
European
puberty onset measurement
Hollis B et al. “Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.” Nature Communications 11(1):1536 (2020)
Allele G
OR 0.02
p 6.0e-18
N 187,241
Large GWAS
European
5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement
Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele G
OR 0.33
p 4.0e-15
N 7,608
Large GWAS
European
X-24494 measurement
Schlosser P et al. “Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.” Nature Genetics 55(6):995-1008 (2023)
Allele G
OR 0.45
p 9.0e-13
N 4,880
Large GWAS
European
5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement
Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele G
OR 0.30
p 4.0e-12
N 7,066
Large GWAS
European
prostate specific antigen amount
Hoffmann TJ et al. “Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups.” Nature Genetics 57(2):334-344 (2025)
Allele C
OR 0.03
p 1.0e-8
N 392,522
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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