rs113038193

This is a regulatory region variant variant in the ARHGAP23 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cerebellar volume measurement

Moberget T et al. “The genetic architecture of human cerebellar morphology supports a key role for the cerebellum in human evolution and psychopathology.” Communications Biology 9(1) (2026)

Allele T

OR —

p 6.0e-9

N 27,302

Large GWAS

European

About ARHGAP23

The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]

View all ARHGAP23 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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