rs1130435

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of gastrotropin in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.12
p 7.0e-86
N 47,745
Large GWAS
European
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Research that mentions this SNP (1)

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Candidate gene association study of type 2 diabetes in a nested case‐control study of the EPIC‐Potsdam cohort – Role of fat assimilation
AssociationN=576Eva Fisher et al.(2007)· Molecular Nutrition &amp; Food Research

Candidate gene association study screening 15 genes involved in fat assimilation for type 2 diabetes susceptibility. In 192 cases and 384 controls from EPIC-Potsdam, six SNPs showed significant associations: FABP6 Thr79Met (rs1130435, OR=0.45, 95% CI 0.22-0.92) showed the strongest protective effect; DBI rs2084202 and rs8192506 (Met71Val), PTGES2 rs13283456 (Arg298His, OR=0.64), SLC27A5 promoter variant (OR=0.54), and novel CLPS Ala109Cys variant (OR=5.83) also associated with diabetes risk. Results provide preliminary evidence for fat assimilation genes in type 2 diabetes susceptibility but require further verification.

Traits studied:Type 2 diabetes
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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